GlucosaminGlucosamine Improves X-Ray Evidence of Arthritis
By Neil Osterweil Medical News
Nov. 15, 1999 (Boston) -- In news that is sure to have dietary supplement makers falling to their knees in thanks, European researchers report on results of a 3-year study indicating that a single daily dose of glucosamine sulfate appears to decrease the progression and ameliorate the signs and symptoms of osteoarthritis of the knee. The findings were presented here Monday at the 63rd Annual Scientific Meeting of the American College of Rheumatology (ACR).
Osteoarthritis is caused by just general wear and tear of the joints. In people who have the condition, the cartilage, the cushion at the end of the bones, deteriorates, which in turn reduces the space between the bones (at the joint), called joint space narrowing, and leads to pain. More than 20 million Americans suffer from the disease; most of them are over 45.
In the study of 212 patients, some took 1,500 mg of glucosamine sulfate orally each day and some took a placebo. X-rays showed that of the patients who took glucosamine sulfate, 22% had X-ray evidence of joint deterioration, compared with 38% of those who took the placebo. At the end of the 3-year study, patients on glucosamine had nearly 50% less joint-space narrowing and experienced significant improvement of symptoms, says Jean-Yves Reginster, MD, PhD, from the University of Liege, Belgium.
"For the first time, we have shown that a compound may be able at least to slow down the progression of osteoarthritis," Reginster says.
Supplement Facts
Each 1/2 ounce (1 tablespoon) contain
Amount per Serving
Glucosamine Sulfate 1000 mg
Chondroitin Sulfate 800 mg
Methylsulfonylmethane (MSM) 500 mg
Vitamin C 250 mg
In a base of:
Purified Water, Natural Orange Flavor, Citric Acid (as a preservative), and Fructose. No artificial flavors or colors.
The statements on this page have not been evaluated by the FDA. This product is not intended to cure, treat or prevent disease.
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